RAF Typhoon fighter aircraft have conducted a mission with France's air force in a coordinated attack targeting an subterranean weapons facility in Syria operated by the IS group, according to the UK's MoD.
The facility, identified by reconnaissance, was believed to be containing munitions and bombs, the release indicated, and was positioned in mountains just above the historic site of Palmyra in the heart of Syria.
"The RAF jets used precision-guided Paveway IV munitions to target a number of approach shafts providing entry to the facility... preliminary assessments are that the strike was effective," the MoD said.
There was no evidence of any harm to civilians in the strike late on Saturday and each participating jet made a safe return, the ministry further stated.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
Daesh - referred to as the so-called Islamic State - established militant control over large swathes of Syria and Iraq prior to its 2019 collapse.
"This operation shows our UK leadership, and determination to work closely with our partners, to eradicate any re-emergence of Daesh and their harmful and extremist ideologies in the Middle East," UK Defence Secretary John Healey said.
RAF aircraft have conducted patrols over Syria to "forestall any efforts to regroup" of the group subsequent to its military defeat at the battle of Baghuz in the year 2019, the authorities noted.
"I extend gratitude to every member of our armed forces participating in this mission for their expertise and their bravery," the Defence Secretary added. "They were part of a great many British personnel stationed over Christmas and New Year. This operation, to eliminate dangerous terrorists who threaten our safety, shows how UK forces are prepared to act, all year round, keeping Britain secure at home and powerful internationally."
In December, the American forces carried out what it called a "massive strike" against IS targets in the country, following an assault resulted in the deaths of two US troops and a civilian linguist in Palmyra.
The U.N. reports Daesh still has an estimated 5,000 to 7,000 combatants in Iraq and Syria.